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We established a differentially weighted model for the improvement activities performance category with two categories, medium and high, to provide flexible scoring and because there are no nationally recognized standards or definitions for these activities (81 FR 28210)

For Bisulfite Sequencing PCR analysis, the means of methylation percentages of each CG locus of MOD, SEV and CTRL groups at endpoints A and B were compared using two-tailed Wilcoxon test and only those that presented a statistically significant difference were considered