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Carbamidomethylcysteine and TMT on Lys and the peptide N-termini were static modifications, while oxidized Met was a variable modification

Moreover, encapsulating mRNA encoding tumor-specific toxic proteins neutrophil elastase (ELANE) or porcine pancreatic elastase (PPE) in lipid nanoparticles to form ELANE or PPE mRNA-LNP can both induce CD8 + T cell infiltration and significantly inhibit tumor growth (148)

Multiple signaling axes ultimately converge on the mitochondrion to jointly regulate the ferroptosis process in BTC

The redox homeostasis that protects from oxidative stress will be enhanced by more glutamate synthesis from glutamine, and more reductive glutamine metabolism promotes lipid biosynthesis that promotes HCC proliferation