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Serotonin syndrome signs and symptoms may include mental status changes (e.g., agitation, hallucinations, delirium, and coma), autonomic instability (e.g., tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, hyperthermia), neuromuscular symptoms (e.g., tremor, rigidity, myoclonus, hyperreflexia, incoordination), seizures, and gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea)

also found that compared to the control group, the serum levels of interleukin (IL)-6 and IL-21 in the primary ovarian failure (POF) group were significantly higher (Sun et al., 2018)

Primers for ITGB7 were: ATCGAGGACAGTGCAACCACGT and TCAGCTCCTCTGAGAAGCCAAG

However, the polyphenols therapeutic potential is becoming more and more evident, enticing the worldwide researchers with a landscape of therapeutic possibilities to uncover the precise and effective biological role of this molecules in counteract oxidative stress, enabling their implementation in preventive healthcare practices, according to the evidence-based dentistry [168]