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Although corticosteroid use in individuals with MMA is associated with risks due to catabolic effects on muscle [21], no notable corticosteroid-related adverse events were observed in this study, even with extended courses of treatment, suggesting that corticosteroids can be safely administered as needed to patients with this condition who are receiving gene editing therapy

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In agreement with this, ATB 0,+ is up-regulated in inflammatory states, such as ulcerative colitis and Crohns disease ( 0,+ with lung bacteria has been suggested as responsible for modulating Pseudomonas aeruginosa attachment to human bronchial epithelial cells with consequent effects on lung disease severity in cystic fibrosis ( Implications of ATB 0,+ in Cancer In the last decade, the over-expression of ATB 0,+ in several human cancers became a hallmark of this pathology similar to what it is described for other plasma membrane transporters (Table 1)

MYC-induced cancer cell energy metabolism and therapeutic opportunities