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JBSNF-000088, a small-molecule analog of NA, is able to be bound to NNMT and to be methylated in the NNMT structure, with SAM being correspondingly demethylated to SAH [58]

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The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, meperidine, methadone, buspirone, amphetamines, and St