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159 Transplantation of the gut microbiota from DSPN patients (but not diabetes patients without neuropathy) into db/db mice treated with antibiotics resulted in exacerbated gutbarrier dysfunction, increased antigen load, systemic inflammation and aggravated peripheral neuropathy

SLC25A20) that is the central component of the mitochondrial carnitine shuttle (Figure 3)

However, the current NBS faces challenges because C0 in days 23 has poor sensitivity and a positive predictive value ( There are some limitations to note about our study