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Non- N -methyl-D-aspartate glutamate receptors mediate oxygenglucose deprivation-induced oligodendroglial injury

Similarly, suppression of the cICD results in a 50% reduction in GSIS in INS-1 832/13 cells and in isolated rat islets [62]

By contrast, LXR inverse agonists, which reduce the basal activity of this constitutively active receptor (favoring interaction with the co-repressor NCOR1), have demonstrated potential in reducing plasma lipids 25 and hepatic fibrosis 28