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For example, ferroptotic macrophages have the ability to generate HMGB1, a DAMP that triggers the release of pro-inflammatory cytokines, including IL-1 and IL-18, and activates the inflammasome (61)

Higher concentration doesn't automatically mean better results and can increase irritation risk

Pathogenetically, the process is initiated by systemic testosterone, which diffuses into prostate stromal cells and undergoes irreversible conversion to dihydrotestosterone (DHT) by type II 5-reductase, the predominant isoform in prostatic tissue

Third, the negative impact of social media comments on the public is very strong, which leads to significant differences in public beliefs in participating in endangered species management (Rodgers and Willcox, 2018)