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The following groups of people are at a greater risk of developing a vitamin B12 deficiency: Vegans or vegetarians People 75+ years Having a digestive system disorder like Crohns or celiac disease Drinking excessive amounts of alcohol Having Sjgrens syndrome Taking certain medications like oral birth control or metformin Common symptoms of a vitamin deficiency include fatigue, numbness, poor balance, memory loss, and breathlessness

The key difference may be that endurance athletes more acutely feel the effects of suboptimal B12 levels during long training sessions

This may be due to the influence of the gut microbiota

There is also a potentially relevant interaction between VEGF and FGF-2, as synergistic action between these two factors has been reported in the literature