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Both antidepressant therapy [512] and zinc supplementation [327] have been found to reduce IL-1 expression and increase Treg levels

In this process, GSH is constantly oxidized to GSSG by the enzyme glutathione peroxidase [Figure - 1]

In addition to their role in the synthesis of eicosanoid acids and SPMs, other metabolites derived from these compounds are also implicated in inflammatory processes