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Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations COX: cytochrome c oxidase CS: citrate synthase CTNS: cystinosin GSH: glutathione GSSG: oxidized glutathione NC: nephropathic cystinosis PG: pyroglutamic acid References Gahl WA, Bashan N, Tietze F, Bernardini I, Schulman JD 1982 Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis

Because peptides are delicate biomolecules composed of amino acid chains, they can degrade if exposed to inappropriate temperatures, moisture, light, or repeated handling

As their names suggest these syndromes are marked by increased oxidative stress and damaged redox states

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