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We report that for three out of four subjects the frequency spectrum of fast rBFI has a clear heart rate peak around 1 Hz for both early and late time gates which matches HR derived from the ECG data

This is not necessarily a negative side effect but rather an indication of accelerated cell turnover, where underlying congestion is brought to the surface as the skin rapidly sheds old cells and regenerates new ones

This helps them assess interactions with your knee surgery, anaesthetic, and recovery medications

Peer review Peer review information Nature Communications thanks Hongli Mao, and the other, anonymous, reviewer for their contribution to the peer review of this work