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Metabolic changes in the psoriatic lesion during therapy

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Rather than functioning as isolated antioxidant modules, these pathways form a highly interconnected redox buffering network in which compensatory capacity, metabolic flux, and iron availability collectively determine ferroptotic susceptibility

Thalassemia is characterized by the defects of one or more hemoglobin chains and phenotypes of the disease ranging from severe anemia to asymptomatic individuals classified as thalassemia major, intermedia, and minor (33, 34)