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de Velasco G, Culhane AC, Fay AP, Hakimi AA, Voss MH, Tannir NM , Tamboli P, Appleman LJ, Bellmunt J, Kimryn Rathmell W, Albiges L, Hsieh JJ, Heng DY, Signoretti S, Choueiri TK

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9 These chronic conditions typically manifest as abdominal pain, bloating, altered bowel movements, and diarrhea, reducing productivity and inflating healthcare costs

discovered that only CCN2 derived from fibroblasts can effectively stimulate the activation of cardiac fibroblasts and promote fibrosis