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Description

Nutrire 43 , 28 (2018)

It has been suggested, based largely on work in animal models, that enduring changes in GABA A Rs expression induced by developmental exposure to steroid hormones, such as progesterone and its metabolites play a role in hippocampal neuronal excitability and in the etiology of sex-dependent neuropsychiatric disorders and memory deficits later in life (209211)

This shift typically leads to inefficient energy production and increased toxic byproducts

Cell culture and differentiation HL-60 cells (CCL-240), obtained from ATCC, were cultured at 37 C with 5% CO 2 in IMDM (Gibco) supplemented with 25 mM HEPES, 2 mM l-glutamine, 20% heat-inactivated fetal bovine serum (FBS) and 1% penicillinstreptomycin