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P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration

Excessive glutamatergic activation of NMDA receptors was shown to increase ROS levels and alter mitochondrial membrane polarity, which led to elevated apoptosis rates in cardiomyocytes, possibly as a result of increased calcium ion influx (Gao et al., 2007)

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Wazir H, Abid M, Essani B, Saeed H, Khan MA, Nasrullah F, Qadeer U, Khalid A, Varrassi G, Muzammil MA, Maryam A, Syed ARS, Shah AA, Kinger S, Ullah F (2023) Diagnosis and treatment of liver disease: current trends and future directions