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However, this energy production naturally generates free radicals as a byproduct

4.6 200 mm ID)

* Correspondence: Zhijun Zhang [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

This energy deficiency directly limits T cell proliferation capacity, thereby weakening their ability to effectively respond to tumor cells and other immune challenges (90)