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It has been proposed that heterodimer formation is restricted to both subunits being from the same class due to dimer interface compatibility interactions

Oxidative stress also activates the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 to regulate the expression of genes that control antioxidant, inflammatory and immune system responses, facilitating GSH activity

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Moreover, conventional techniques are often time-consuming and yield low rates of polysaccharide recovery while frequently necessitating multiple rounds of extraction