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The patients were recruited at FMT-HVD, Manaus, Amazonas, and the following inclusion criteria were applied: over 18 years of age, a positive microscopy diagnosis for P

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Given the heterogeneity of genetic mutations (which can take place in different positions along the DNA, thus in different genes) and the resulting increasing number of genetic mouse models that have been generated, different animal models reproduce various aspects of ASD symptomatology, with the best animal model keeping together all three types of validity criteria