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When disruption of the tear layer occurs, either to inadequate tear production or excessive water evaporation, the eyes lose one of their protective barriers and become prone to weather changes or external factors

Tumor necrosis factor alpha (TNF-), interferon gama (IFN-), and interleukin (IL)-8 which are secreted by T lymphocytes, keratinocytes and inflammatory cells polarize type 1 T lymphocytic pathway and lead to the migration of polymorphonuclear leukocytes to the epidermis predominantly [2]

Methods We applied the Navigation Guide methodology to the scientific literature to comprehensively and objectively examine the association between prenatal acetaminophen exposure and NDDs and related symptomology in offspring

Missing weeks disrupts the cumulative benefit