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The Role of NCOA4-Mediated Ferritinophagy in Ferroptosis

4.1.3 Histological examination of tumor tissues The tumor histopathological examination of mice in the SEC control group showed solid sheets of malignant tumor cells

In fact, transgenic mice overexpressing NGF display elevated GSH concentrations in the plasma, brain, and liver ( Here, we document that a systemic reduction of GSH levels, up-regulates the transcription of L-cys/L-cys 2 and glutamate AA transporters and antioxidant genes in the striatum trough the TrkA/Akt pathway, which was mediated, at least in part, by peripheral NGF levels