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These properties underlie its efficacy in mitigating tissue destruction in periodontal disease, reducing oral mucosal erythema and ulceration, and protecting against the carcinogenic progression of precancerous lesions by preventing oxidative DNA damage

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The drug creates a positive feedback loop where weight loss improves the metabolic environment, which makes further metabolic normalization easier

However, that ratio drops to 10 or less in susceptible cells exposed to oxidative stress