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The upregulation of ACSL4 increased Arachidonoyl-Phosphatidylethanolamine (AA-PE) and Adrenoyl-Phosphatidylethanolamine (AdA-PE) levels, promoted ferroptosis, and exacerbated tubular fibrosis in DKD (122)

WHO [online], (2015)

Hyphenated Page 92 and 93: Liu T, Li L, Teng X, Huang X, Liu H Page 94 and 95: Maitra A

Moreover, 50 or 100 mg/kg of luteolin has been found to markedly attenuate DSS-induced murine colitis symptoms compared with a DSS group, primarily by inhibiting JNK1/2, phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling, NF-B and STAT3 pathways to exert anti-inflammatory, anti-apoptotic and anti-autophagic effects for colonic homeostasis restoration (68)