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This is a later complication of under treated B12 deficiency and something that not many GP's will be aware of

CrossRef The Immunomodulatory and Regenerative Effect of Biodentine on Human THP1 Cells and Dental Pulp Stem Cells: In Vitro Study Duaa Abuarqoub, Nazneen Aslam, Rand Zaza, Hanan Jafar, Suzan Zalloum, Renata Atoom, Walhan Alshaer, Mairvat Al-Mrahleh, Abdalla Awidi, Bruna Sinjari BioMed Research International.2022;[Epub] CrossRef Biodentine: Material of choice for apexification Himanshu Aeran, Mahema Sharma, Avantika Tuli International Journal of Oral Health Dentistry.2021