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Downstream costs : All reported downstream costs are based on assumptions of population trends (i.e., incidence, prevalence, and mortality rates), time horizon, resource utilization, patient compliance, health care patterns, market trends (i.e., rates of intervention uptake or trends in current programs in place in the province), and estimates of funding and prices

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Both are derived from human growth hormone (HGH) and have been extensively studied in laboratory environments for their role in understanding fat metabolism, cellular energy regulation, and peptide-receptor interactions