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We have found, by simulation, that if we reduce the amino acid input into the system by 15%, the concentration of GSH and the synthesis rate of GSH are proportionally diminished, but there is little effect on the DNA methylation reaction, while reactions in the folate cycle are reduced by 29%

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Endogenous retroelements and the host innate immune sensors

The link between DNA damage and autophagy in thyroid cancer cells during ferroptosis has not yet been explored, and future mechanistic studies are needed to understand the exact relationship between the autophagy and DNA damage