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Even if COPD is heterogenous in its manifestations, it usually includes two major pathologies: small airway disease with peribronchiolar fibrosis and emphysema with alveolar wall destruction [15]

[8] The rate of weight reduction in test subjects was consistently compared to the placebo cohort, and weight loss appeared to hold steady over the entire study period

However, it still need further addressed whether there is an enhanced sprouting or an protect effect of existing axon