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Type 1 diabetes, which is characterized by insulin deficiency, results in reduced cardiac glucose uptake and oxidation, as the hearts glucose regulation is primarily insulin dependent

The N-methyl-d-aspartate (NMDA) receptor-mediated excitatory procedure, which provides the intracellular Ca2+ increase necessary for nNOS activation, is another mechanism by which UCB-induced neuronal damage occurs

[77] [78] Other NAD-dependent enzymes include bacterial DNA ligases, which join two DNA ends by using NAD + as a substrate to donate an adenosine monophosphate (AMP) moiety to the 5' phosphate of one DNA end

Regulation of GSK3/Nrf2 signaling pathway modulated erastin-induced ferroptosis in breast cancer