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Short-chain fatty acids (such as acetic acid) are significantly reduced in the gut microbiota of RA patients, leading to OR51E2 ligand deficiency (6769)

The metabolic kynurenic pathways is likely also implicated in ME/CFS, owing to common mutations in IDO2 (76) such as R248W and Y359STOP (77)

Assessment of causal direction between gut microbiota-dependent metabolites and cardiometabolic health: A bidirectional mendelian randomization analysis

In PCI, the narrowed coronary artery is opened by placing stents, whereas in CABG, a bypass is created around the blocked artery using a vessel from another part of the body