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International journal of endocrinology, 201

While this unidirectional behavior effectively destroys cell metabolism for tumor suppression, it poses challenges because of the absence of coupling between the intracellular nanostructures and endogenous feedback mechanisms, thereby hindering their translation to scenarios requiring sustained cellular viability and precise, nondestructive function modulation, including probiotic interventions 46 , programmable cell-based therapeutics 47 and engineered living materials 48

Vitamin C can counteract the consequences of long-term alterations that can generate free radicals, even though these effects have been shown to inhibit the production of antioxidant defense, lower proteolytic activity, and encourage the buildup of oxidized proteins (78, 79)

Therefore, the search is iterated many times until no more unique trees can be constructed