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10.3390/antiox12101867 114 TosiG

In 65 clinical cases of neurogenic cervical spondylosis, after taking Ershiwuwei Shanhu pills orally combined with acupuncture based on the condition for one course of treatment, the pain symptoms were significantly reduced, and after two courses, the symptoms disappeared completely, and no recurrence was seen thus far (Zhang and Zhang, 2011)

In contrast, knockdown of TfR1 in BJ-TERT/LT/ST/RAS V12 cells partially inhibited ferroptosis induced by erastin [10] Related studies have confirmed that the JNK/p38MAPK pathway plays a role in erastin-induced ferroptosis in HL-60/NRAS Q61L cells and that activation of JNK/p38MAPK, an upstream signaling pathway of TfR1, can upregulate the expression level of TfR1 [25]