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Folates can resist heat degradation in anaerobic conditions, while they are degraded in the presence of oxygen

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For patients with Brugada syndrome, Quinidine is an alternative to implantable cardioverter-defibrillator (ICD) placement (66) This class has also shown utility in individuals with short QT syndrome experiencing recurrent ventricular arrhythmias (VAs), reducing the frequency of ICD shocks in these patients (66)