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Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements

Vasopressor infusion rates were substantially reduced in five patients, unchanged in one patient, and increased in one patient while maintaining a stable or improved MAP

However, the structure of TauT remains unknown, precluding a thorough understanding of its transport mechanism and the structure-based development of medications

[DOI] [PubMed] [Google Scholar] 41.Ferner RE, Dear JW, Bateman DN