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Research has found that mast cells also have the ability to synthesize and store thyroid hormones like T3 and TSH, suggesting that mast cells can modulate thyroid function, and an increase of mast cells has been observed in cases of hypothyroidism

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Colorectal cancer cells with a low NMNAT2 expression have demonstrated resistance to tiazofurin, which could be reversed by overexpressing NMNAT2 in tiazofurin-resistant colorectal cancer cell lines [158]