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NOTE: Without other existing deficits: Mild impairment of thumb adduction equals a 712% loss of use of the thumb

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If you are experiencing pain, a visible bulge, or discomfort from a hernia, an evaluation by a qualified surgeon can help determine the best treatment plan

Together these observations are consistent with an important concept: microglia are the earliest responders to a primary multifocal myelin injury in the MS white matter, and importantly, this injury/response seems to precede lymphocytic infiltration, arguing against adaptive immune cells being the primary drivers of white matter injury