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After incubation, the cells were stimulated using 1 g/mL LPS, and the stimulated cells were then treated with non-toxic concentrations of APE, GSH and DEX as a reference control

Chronic stress, environmental toxins, diets low in nutrients but high in inflammatory triggers, sleep deprivation, smoking, sugar, excess alcohol, and other stressors slowly deplete glutathione levels

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Moreover, HPA axis dysregulation is implicated in many physical and psychiatric disorders [46] that can be triggered or exacerbated by stress, and related neuroimaging alterations are not disease-specific