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In this context, glutathione S-transferases (GSTs) finds an important mention as members of this family quench reactive molecules and catalyze the conjugation of GSH to an array of hydrophobic and electrophilic substrates, thus, protecting the cell from oxidative burst

The available data suggest that beginning at low doses (e.g., 10 mg) and titrating gradually to 75-100 mg if tolerated is an acceptable dosing regimen

Unlike fat-soluble vitamins that accumulate in your body, excess water-soluble vitamins are excreted through your urine

This process is particularly pronounced when glutathione (GSH) is depleted or glutathione peroxidase 4 (GPX4), a key enzyme that prevents lipid oxidation, is inhibited [39]