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It is studied in preclinical models to investigate selective lipolysis stimulation, adipocyte metabolism regulation, body composition effects, and metabolic parameter modulation

Based on current clinical evidence, the rough ordering from largest to smallest weight-loss effect is: Tirzepatide highest average weight loss Semaglutide significant weight loss Tesamorelin moderate weight loss, primarily through visceral fat reduction AOD-9604 primarily body composition effects MOTS-c primarily metabolic and energy effects rather than pure weight reduction AOD-9604 and MOTS-c are generally not considered replacements for GLP-1 medications in patients seeking substantial weight reduction

Dosage and frequency of administration may vary based on the individual pet and prescriber