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It involves the coordinated interaction of multiple biological processes, including: Cell migration to the site of injury Formation of new blood vessels (angiogenesis) Fibroblast activation Extracellular matrix remodeling Regulation of the inflammatory response Cytoskeletal organization For this reason, research is increasingly focused on combining peptides that possess distinct yet complementary mechanisms of action

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Mechanism five: electrolyte depletion and loss of membrane stability Magnesium sits inside the NMDA receptor channel, competes with calcium at VGCC binding sites, and stabilizes cell membranes and the sodium-potassium pump