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The transgenic expression time of adenovirus as a gene vector is short, and can trigger the immune response of the host

31 It primarily signals through ET A receptors (ET A Rs) on vascular smooth muscle, triggering inflammation and cell growth

We systematically compared molecular signatures of APOE4 and APOE2 carriers, anchoring analyses on AD diagnosis and A status to distinguish dominant genotype effects from disease-driven protein alterations within an upstream ( APOE protein AD/A) versus downstream ( APOE AD/A protein) mediation framework