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Most recently, the ClearPoint system is being used with MRI-compatible materials for stereotactic localization with intraoperative imaging so that injection into the targeted structures can be visualized directly if the therapy is labeled with contrast agent

328 In ALS, HSBP8 protects against aggregation of TDP-43 and its cleavage products (TDP-25 and TDP-35) by promoting their removal via autophagy, further illustrating the tight functional coupling between sHSPs and degradative pathways

Both ALA and its reduced form DHLA act as potent antioxidants, capable of scavenging reactive oxygen species in various cellular compartments

These results conclusively demonstrate that, in the absence of NTRC, a portion of GSAAT At remains in the oxidized form