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Description

Clinicians should screen each patient for metabolic, endocrine, and cardiovascular factors to ensure safe use

Key pathways: GLP-1 receptor activation Ghrelin suppression Amylin pathway reinforcement 2

Its primary pharmacological characterization was published in European Journal of Endocrinology (PMID 9849822), where the authors identified it as the first growth-hormone-secretagogue receptor (GHSR-1a) agonist achieving GH-release selectivity comparable to GHRH in animal models