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Muller et al., 2011

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Identification and expert curation of compounds acting on oligodendroglial-associated genes We then queried SPIED with our oligodendroglial signature to obtain small bioactive molecules (compounds) inducing similar transcriptional changes and found a large number (449) of positively associated compounds

Poster Session II - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.01 - ACUTE MANAGEMENT - Neither thrombolysis nor thrombectomy P665 - ESOC25-1833 STA-MCA BYPASS IN ACUTE STROKE PATIENTS: THE ZURICH EXPERIENCE Martina Sebk 1 , Jorn Fierstra 1 , Zsolt Kulcsar 2 , Susanne Wegener 3 , Luca Regli 1 , Giuseppe Esposito 1 1 Department of Neurosurgery, University Hospital Zurich, Zurich, Switzerland, 2 Department of Neuroradiology, University Hospital Zurich, Zurich, Switzerland, 3 Department of Neurology, University Hospital Zurich, Zurich, Switzerland Background and Aims: The concept of penumbra salvage can be applied to surgical revascularization with bypass in carefully selected patients