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The results demonstrated that hesperidin supplementation resulted in significant reductions in fasting glucose levels, triglycerides, systolic blood pressure, TNF- and hs-CRP levels as compared to the placebo group

Use niacin with caution in patients with a past history of peptic ulcer disease or in those on maintenance therapy to prevent PUD recurrence

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[2] Aronne LJ, Bade Horn D, le Roux CW, Ho W, Falcon BL, Gomez Valderas E, Das S, Lee CJ, Glass LC, Senyucel C, Dunn JP