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Results We demonstrated that this peptide-liposome-small molecule machinery targets AML and consequently induces cell apoptosis both in vitro and in vivo through three disparate mechanisms: (I) Oridonin, as a Michael acceptor molecule, inhibits GSH function through covalent bonding, triggering an initial imbalance of oxidative stress

In addition, when copper peptides are injected into the dermis, approximately 95 % of the peptides are excreted by the body [33,34]

[0001739] A pharmaceutical composition for topical administration may comprise at least one inactive ingredient

As to ligands, their frustrating elements are the drivers, which can exert attractive pulling or repulsive pushing interactions and anchors at the allosteric sites (Nussinov and Tsai, Reference Nussinov and Tsai2014b)