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Reward Pathways: GLP-1 RAs modulate the mesolimbic reward system (including the ventral tegmental area and nucleus accumbens), potentially reducing the hedonic drive to consume palatable foods and even moderating addictive behaviors (Zheng et al., 2024)

If you're using a multi-use compounded medication vial for semaglutide or tirzepatide, make sure you understand what your prescribed dose is

Some studies indicate that an overload of antioxidants, including glutathione, could potentially lead to an imbalance in this delicate system

Consistently, using the dual nanosensor approach, the [ATP] c in cultured cortical astrocytes was estimated as 1.5 mM, while the concentration in astrocytes in acute cortical slices was calculated to be in the range between 0.7 mM and 1.3 mM [64]