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Consequently, its activity reflects the cells energy state and redox balance and can modulate mitochondrial ROS production under conditions of high NADH/NAD + ratios or impaired electron flow

Similar content being viewed by others Introduction Altered intestinal microbiota composition, termed dysbiosis, is associated with autoimmune diseases, particularly type 1 diabetes 1 , multiple sclerosis 2 , systemic lupus erythematosus 3 and rheumatoid arthritis (RA) 4,5