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doi: 10.1007/978-3-642-33989-9_15 Mobli, Mehdi, Hoch, Jeffrey C

Raw sequencer reads were processed using Illuminas RTA and CASAVA pipeline software that includes image analysis, sequence quality scoring, and base calling

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Importantly, KRAS-dependent NSCLC cells that were hypersensitive to LDHB/SLC7A11 inhibition (A549, H460, H2122, H838, H2009, KP) exhibited high levels of NRF2 or NRF2 score based on prior studies [57, 58], whereas the outliers (H358, H23, and Calu-1), in which LDHB KD failed to sensitize the cells to Erastin or RSL3, are characterized by low NRF2 levels