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Many growth factors such as transforming growth factor (TGF)-, 2 platelet-derived growth factor (PDGF), 3 epidermal growth factor (EGF), 4 and fibroblast growth factor (FGF), 5 as well as interleukin (IL)-1 6 and tumor necrosis factor (TNF), 7 have been evaluated in a wide spectrum of in vivo and in vitro experiments to observe their effects on different elements included in the healing process

These findings raise important questions about what makes digital technologies increasingly valuable in the rare disease trial landscape, and what benefits they offer beyond logistical convenience

Each vial holds a single dose of the drug

The thumb comprises of 2 small bones known as phalanges