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Methods: Micropatterned PHH islands, generated using soft lithography, were surrounded by 3T3-J2 fibroblasts (MPCC) +/- activated hepatic stellate cells (HSCs) to generate stellate cell-containing micropatterned tri-cultures (S-MPTCs)

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Such pain can be caused by damage to the central or peripheral nervous system, diabetes, metabolic disorders, viral infections, nutritional deficiencies, trauma, and physical injuries (Fonseca-Rodrigues et al., 2021)